α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels.

α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels.
Related Articlesα-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels. Elife. 2021 Feb 15;10: Authors: Jacob RS, Eichmann C, Dema A, Mercadante D, Selenko P Abstract The Parkinson's disease protein α-synuclein (aSyn) promotes membrane fusion and fission by interacting with various negatively charged phospholipids. Despite postulated roles in endocytosis and exocytosis, plasma membrane (PM) interactions of αSyn are poorly ... read more
Source: PubMedPublished on 2021-02-16