3D Structure of Brain Alpha-Synuclein More Heterogeneous Than Previously Thought, New Study Reports

3D Structure of Brain Alpha-Synuclein More Heterogeneous Than Previously Thought, New Study Reports
Clumps, or aggregates of alpha-synuclein protein in the brain, a hallmark of Parkinon’s disease, are more heterogeneous than previously thought, according to a new study. Moreover, the protein’s 3D-structure is different in Parkinson’s patients as compared with lab-made versions. These findings may hold implications for the development of treatments targeting alpha-synuclein, as new therapies need to take into account what ... read more
Source: Parkinson’s News TodayPublished on 2019-12-12By Patricia Inacio, PhD