A multicentre validation study of the diagnostic value of plasma neurofilament light

A multicentre validation study of the diagnostic value of plasma neurofilament light
Nat Commun. 2021 Jun 7;12(1):3400. doi: 10.1038/s41467-021-23620-z.ABSTRACTIncreased cerebrospinal fluid neurofilament light (NfL) is a recognized biomarker for neurodegeneration that can also be assessed in blood. Here, we investigate plasma NfL as a marker of neurodegeneration in 13 neurodegenerative disorders, Down syndrome, depression and cognitively unimpaired controls from two multicenter cohorts: King's College London (n = 805) and the Swedish BioFINDER ... read more
Source: PubMedPublished on 2021-06-08By Nicholas J Ashton