A review of the current research on in vivo and in vitro detection for alpha-synuclein: a biomarker of Parkinson’s disease

A review of the current research on in vivo and in vitro detection for alpha-synuclein: a biomarker of Parkinson’s disease
Anal Bioanal Chem. 2023 Jan 23. doi: 10.1007/s00216-023-04520-1. Online ahead of print.ABSTRACTParkinson's disease is a health-threatening neurodegenerative disease of the elderly with clinical manifestations of motor and non-motor deficits such as tremor palsy and loss of smell. Alpha-synuclein (α-Syn) is the pathological basis of PD, it can abnormally aggregate into insoluble forms such as oligomers, fibrils, and plaques, causing degeneration ... read more
Source: PubMedPublished on 2023-01-23By Rui Wang