A Sparse Mixture-of-Experts Model With Screening of Genetic Associations to Guide Disease Subtyping

A Sparse Mixture-of-Experts Model With Screening of Genetic Associations to Guide Disease Subtyping
Front Genet. 2022 Jun 6;13:859462. doi: 10.3389/fgene.2022.859462. eCollection 2022.ABSTRACTMotivation: Identifying new genetic associations in non-Mendelian complex diseases is an increasingly difficult challenge. These diseases sometimes appear to have a significant component of heritability requiring explanation, and this missing heritability may be due to the existence of subtypes involving different genetic factors. Taking genetic information into account in clinical trials might ... read more
Source: PubMedPublished on 2022-06-23By Marie Courbariaux