ALDH1A1 Genetic Variations May Modulate Risk of Parkinson’s Disease in Han Chinese Population

ALDH1A1 Genetic Variations May Modulate Risk of Parkinson’s Disease in Han Chinese Population
Front Neurosci. 2021 Mar 19;15:620929. doi: 10.3389/fnins.2021.620929. eCollection 2021.ABSTRACTBackground: Studies in animal models have suggested that aldehyde dehydrogenase 1 (encoded by ALDH1A1) protects against Parkinson's disease (PD) by reducing toxic metabolites of dopamine. Herein we aimed to investigate whether ALDH1A1 was genetically associated with PD susceptibility in humans. Methods: A Han Chinese population of 1,039 subjects was recruited to analyze ... read more
Source: PubMedPublished on 2021-04-05By Hui-Hui Fan