APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson’s Disease

APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson’s Disease
Front Neurol. 2021 Feb 5;12:631145. doi: 10.3389/fneur.2021.631145. eCollection 2021.ABSTRACTIntroduction: Cognitive decline and dementia are common and debilitating non-motor phenotypic features of Parkinson's disease with a variable severity and time of onset. Common genetic variation of the Apolipoprotein E (APOE) and micro-tubule associated protein tau (MAPT) loci have been linked to cognitive decline and dementia in Parkinson's disease, although studies have ... read more
Source: PubMedPublished on 2021-02-22By Jon-Anders Tunold