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• Astrocytes to Dopamine Neurons in One Step June 25, 2020 Parkinson's is a neurodegenerative condition, resulting in the loss of specific types of nerve cells from the brain. The 'motor symptoms' of Parkinson's are associated with a reduction in the number of these nerve cells (or neurons) that produce the chemical 'dopamine' in the mid-brain. For a long time, researchers have been experimenting with different methods to replace these lost…
• Astrocytes to Dopamine Neurons in One Step June 25, 2020 Parkinson's is a neurodegenerative condition, resulting in the loss of specific types of nerve cells from the brain. The 'motor symptoms' of Parkinson's are associated with a reduction in the number of these nerve cells (or neurons) that produce the chemical 'dopamine' in the mid-brain. For a long time, researchers have been experimenting with different methods to replace these lost…
• Dopamine Replacement Cell Therapies - Research Updates April 1, 2019 Stem Cell Therapies for Parkinson's Although the underlying cause of Parkinson's is unknown, scientists do know that Parkinson's results from the impairment and loss of dopamine producing cells in an area of the brain called the substantia nigra. It stands to reason therefore that replacement of those cells is a viable and potentially potent treatment method. Although it is acknowledged…
• Dopamine Cell Replacement Therapies - Research Updates May 15, 2019 YouTube Video https://www.youtube.com/watch?v=fOa21v8MpGw Stem Cell Therapies for Parkinson's Although the underlying cause of Parkinson's is unknown, scientists do know that Parkinson's results from the impairment and loss of dopamine producing cells in an area of the brain called the substantia nigra. It stands to reason therefore that replacement of those cells is a viable and potentially potent treatment method. Although…
• Dopamine Cell Replacement Therapies - Research Updates May 9, 2019 YouTube Video https://www.youtube.com/watch?v=fOa21v8MpGw Stem Cell Therapies for Parkinson's Although the underlying cause of Parkinson's is unknown, scientists do know that Parkinson's results from the impairment and loss of dopamine producing cells in an area of the brain called the substantia nigra. It stands to reason therefore that replacement of those cells is a viable and potentially potent treatment method. Although…
• Stem Cell (Dopamine Cell Replacement) Therapies For Parkinson's July 24, 2019 YouTube Video https://www.youtube.com/watch?v=fOa21v8MpGw Stem Cell Therapies for Parkinson's Although the underlying cause of Parkinson's is unknown, scientists do know that Parkinson's results from the impairment and loss of dopamine producing cells in an area of the brain called the substantia nigra. It stands to reason therefore that replacement of those cells is a viable and potentially potent treatment method. Although…
• GDNF and Cell Transplantation: Dual therapies for Parkinson's February 24, 2020 Parkinson's is a complex condition and it is becoming increasingly clear that the future of disease-modifying therapies for Parkinson's will rely on the use of multiple treatment approaches, as opposed to a single therapy. Scientists in Australia have recently published pre-clinical research exploring this idea - and assessing the effects of treating models of Parkinson's with a combination of different…
• GDNF and Cell Transplantation: Dual therapies for Parkinson's February 25, 2020 Parkinson's is a complex condition and it is becoming increasingly clear that the future of disease-modifying therapies for Parkinson's will rely on the use of multiple treatment approaches, as opposed to a single therapy. Scientists in Australia have recently published pre-clinical research exploring this idea - and assessing the effects of treating models of Parkinson's with a combination of different…
• Bayer Buys Blue Rock August 15, 2019 Last week the large pharmaceutical company Bayer announced they will be buying the biotech firm 'BlueRock Therapeutics'. This move may have important implications for the Parkinson's community. Parkinson's is characterised by the loss of dopamine neurons in the brain and for a long time scientists have been researching different methods of re-introducing these cells into the brain. One example of…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons April 4, 2018 Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal…
• Fluke Discovery Finds Mature Mouse Neurons Can Be Reprogrammed, Researchers Report October 19, 2018 While attempting to transform a type of brain cell into neurons, researchers instead discovered they can turn mature neurons — which were previously believed to be unchangeable — into neurons that produce dopamine, the neurotransmitter that is lost in Parkinson’s disease. The incidental discovery has therapeutic implications for Parkinson’s and other neurological conditions, according to the team at the  University of Texas…
• New Purification Method May Improve Stem Cell Replacement Therapy for Parkinson’s August 28, 2018 A new process to select and purify stem cells that hold therapeutic potential to replace dopamine-producing neurons may hasten clinical development of this promising avenue to treat Parkinson’s disease. Upon being transplanted, these cells promoted dopamine production and reduced the severity of disease-related motor symptoms in an animal model of Parkinson’s disease. The pre-clinical study with that finding, “Discovery of…
• Breakthrough in stem cell treatment for Parkinson's February 25, 2018 In a major breakthrough for the treatment of Parkinson's disease, researchers working with laboratory rats show it is possible to make dopamine cells from embryonic stem cells and transplant them into the brain, replacing the cells lost to the disease. Researchers say it is possible to make dopamine cells from human embryonic stem cells, paving the way for a new…