Atomistic Simulation Tools to Study Protein Self-Aggregation.

Atomistic Simulation Tools to Study Protein Self-Aggregation.
Related ArticlesAtomistic Simulation Tools to Study Protein Self-Aggregation. Methods Mol Biol. 2019;2039:243-262 Authors: Meneksedag-Erol D, Rauscher S Abstract Aberrant aggregation of proteins into poorly soluble, toxic structures that accumulate intracellularly or extracellularly leads to a range of disease states including Alzheimer's, Parkinson's, Huntington's, prion diseases, and type II diabetes. Many of the disease-associated amyloidogenic proteins are intrinsically disordered, which makes ... read more
Source: PubMedPublished on 2019-07-26