Bacterial Butyrate in Parkinson’s Disease Is Linked to Epigenetic Changes and Depressive Symptoms

Bacterial Butyrate in Parkinson’s Disease Is Linked to Epigenetic Changes and Depressive Symptoms
Mov Disord. 2022 Jun 20. doi: 10.1002/mds.29128. Online ahead of print.ABSTRACTBACKGROUND: The gut microbiome and its metabolites can impact brain health and are altered in Parkinson's disease (PD) patients. It has been recently demonstrated that PD patients have reduced fecal levels of the potent epigenetic modulator butyrate and its bacterial producers.OBJECTIVES: Here, we investigate whether the changes in the gut ... read more
Source: PubMedPublished on 2022-06-20By Aoji Xie