Basic Leucine Zipper Protein Nuclear factor erythroid 2-related factor 2 as a Potential Therapeutic Target in Brain Related Disorders

Basic Leucine Zipper Protein Nuclear factor erythroid 2-related factor 2 as a Potential Therapeutic Target in Brain Related Disorders
Protein Pept Lett. 2022 Jun 22. doi: 10.2174/0929866529666220622124253. Online ahead of print.ABSTRACTNuclear factor erythroid-2-related factor 2 (Nrf2), an inducible transcription factor in phase II metabolic reactions as well as xenobiotic response pathway referred to as 'master regulator' in anti-oxidant, anti-inflammatory, and xenobiotic detoxification processes. The activity of Nrf2 is tightly regulated by KEAP1, which promotes ubiquitination followed by degradation under ... read more
Source: PubMedPublished on 2022-06-23By Ahsas Goyal