Beauty and death of motion

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• The road ahead: 2022 January 20, 2022 # # # # The first post at the start of each year on the SoPD website tries to provide an overview of where things are in the search for ‘disease modifying’ therapies for Parkinson’s.  It is an exercise in managing expectations as well as discussing what research events are scheduled for the next year so that we can keep…
• The road ahead: 2021 January 25, 2021 # # # # At the start of each year, it is a useful practise to layout what is planned over the next 12 months. The events that are scheduled for the year to come, so that we can keep an eye out for them. Obviously, where 2021 will end actually is unpredictable, but an outline of what is scheduled…
• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
• EJS-ACT PD June 26, 2021 # # # # This week an announcement was made regarding The Edmond J. Safra Accelerating Clinical Treatments for Parkinson’s Disease (EJS-ACT PD) Initiative. It is hoping to revolutionise the way clinical trials for potentially disease-modifying drugs for Parkinson’s are conducted. The project is focused on the setting up a multi-arm, multi-stage (MAMS) platform for evaluating new therapies for PD.…
• Beauty and death of motion March 17, 2023 J Clin Neurosci. 2023 Mar 15;111:37-38. doi: 10.1016/j.jocn.2023.03.004. Online ahead of print.ABSTRACTTranslational research aims to apply what we learn in the lab to the patient's care in the clinical setting. Animal studies for Parkinson's disease and Deep Brain Stimulation (DBS) are particularly intriguing topics that show the value of translational research. Training a monkey to complete a task, inducing Parkinsonian…
• Beauty and death of motion March 17, 2023 J Clin Neurosci. 2023 Mar 15;111:37-38. doi: 10.1016/j.jocn.2023.03.004. Online ahead of print.ABSTRACTTranslational research aims to apply what we learn in the lab to the patient's care in the clinical setting. Animal studies for Parkinson's disease and Deep Brain Stimulation (DBS) are particularly intriguing topics that show the value of translational research. Training a monkey to complete a task, inducing Parkinsonian…
• Beauty and death of motion March 17, 2023 J Clin Neurosci. 2023 Mar 15;111:37-38. doi: 10.1016/j.jocn.2023.03.004. Online ahead of print.ABSTRACTTranslational research aims to apply what we learn in the lab to the patient's care in the clinical setting. Animal studies for Parkinson's disease and Deep Brain Stimulation (DBS) are particularly intriguing topics that show the value of translational research. Training a monkey to complete a task, inducing Parkinsonian…
• Monthly research review: February 2020 February 29, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during February 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Other news Review…
• Monthly Research Review – December 2021 December 31, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during December 2021. The post is divided into 10 parts based on the type of research: Top 5 pieces of Parkinson’s news Articles of general interest Basic biology…
• Monthly Research Review – July 2021 July 31, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during July 2021. The post is divided into 10 parts based on the type of research: Top 5 pieces of Parkinson’s news Articles of general interest Basic biology…
• Monthly Research Review – December 2020 December 31, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during December 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Conferences/lectures Other news…
• 2020: Year in Review January 1, 2021 # # # # In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2020. Month-by-month we will briefly discuss some of the major pieces of research/ announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies…
• Can shaking hands fix shaking hands? December 5, 2022 # # # # Novel treatments for Parkinson’s are being proposed on a regular basis, and I really like the way many are based on some pretty left field ideas (light buckets, I’m thinking of you here). Thinking outside the box is important to innovation and progress. And some of those unconventional approaches are backed not only by historical precedent,…
• The Bluerockers have started July 15, 2021 # # # # On the 8th June, BlueRock Therapeutics put out a press release announcing that the first participant in their Phase I clinical trial of cell transplantation for Parkinson’s had been dosed (Click here to read the press release). The initiation of this clinical trial by the company is a major step forward for them and for the…
• Speech, Voice & Parkinson’s Q&A with John Dean January 28, 2021 We recently hosted a webinar with speech-language pathologist John Dean. You can get access to the recording here. We received so many questions during the session that we weren’t able to answer them all; so, John was kind enough to do some written Q&A for us. “When is a good time to start speech therapy?” It’s much better to maintain…
• Monthly Research Review – November 2020 November 30, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during November 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Conferences/lectures Other news…
• Monthly Research Review: January 2022 January 31, 2022 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during January 2022. The post is divided into 10 parts based on the type of research: Top 6 pieces of Parkinson’s news Articles of general interest Basic biology…
• The drug development pipeline for Parkinson’s December 2, 2020 # # # # For a long time a regular request from SoPD readers has been to provide an overview of the clinical trial landscape for Parkinson’s, particularly in the area of drug development. Such projects are difficult, however, as the landscape is broad and dynamic – lots of different approaches being applied and new entrants continually entering the arena.…
• Monthly Research Review – October 2022 October 31, 2022 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during October 2022. The post is divided into 10 parts based on the type of research: Top 5 pieces of Parkinson’s news Articles of general interest Basic biology…
• Mind blowing modulation of mind October 12, 2021 # # # # Neuromodulation of specific circuits in the brain represents a means of adjusting deficits in neural performance and significantly improving quality of life. Deep brain stimulation has been widely applied to the treatment of Parkinson’s since Alim Benabid first discovered that electrical stimulation of the basal ganglia improves the symptoms of the condition in the late 1980s.…
• Deep Brain Stimulation for Parkinson’s - An Update February 1, 2019 (Guest post by Dr. Eric Rhoden, PT, DPT)Until recently deep brain stimulation (DBS) for Parkinson’s Disease has been a monopolized industry run and operated by Medtronic, who has produced an amazing device that has changed countless lives. However, technology has developed at a rapid pace over the last year, and now there are more options to be aware of when…
• Monthly research review – March 2021 March 31, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during March 2021. The post is divided into ten parts based on the type of research: Top 5 pieces of Parkinson’s news Articles of general interest Basic biology…