Bioactivity of the cannabigerol cannabinoid and its analogues – the role of 3-dimensional conformation

Bioactivity of the cannabigerol cannabinoid and its analogues – the role of 3-dimensional conformation
Org Biomol Chem. 2023 May 24. doi: 10.1039/d3ob00383c. Online ahead of print.ABSTRACTCannabinoids are naturally occurring bioactive compounds with the potential to help treat chronic illnesses including epilepsy, Parkinson's disease, dementia and multiple sclerosis. Their general structures and efficient syntheses are well documented in the literature, yet their quantitative structure-activity relationships (QSARs), particularly 3-dimensional (3-D) conformation-specific bioactivities, are not fully resolved. ... read more
Source: PubMedPublished on 2023-05-24By Mohammed Salha