Brain-wide transcriptome-based metabolic alterations in Parkinson’s disease: human inter-region and human-experimental model correlations

Brain-wide transcriptome-based metabolic alterations in Parkinson’s disease: human inter-region and human-experimental model correlations
Mol Omics. 2023 Mar 17. doi: 10.1039/d2mo00343k. Online ahead of print.ABSTRACTAlterations in brain metabolism are closely associated with the molecular hallmarks of Parkinson's disease (PD). A clear understanding of the main metabolic perturbations in PD is therefore important. Here, we retrospectively analysed the expression of metabolic genes from 34 PD-control post-mortem human brain transcriptome data comparisons from literature, spanning multiple ... read more
Source: PubMedPublished on 2023-03-17By Regan Odongo