C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson’s disease.

C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson’s disease.
Related ArticlesC-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease. J Biol Chem. 2019 May 15;: Authors: McGlinchey RP, Lacy SM, Huffer KE, Tayebi N, Sidransky E, Lee JC Abstract A pathological feature of Parkinson's disease (PD) is Lewy bodies (LBs) composed of α-synuclein (α-syn) amyloid fibrils. α-Syn is 140-amino-acids long protein, but truncated α-syn is enriched ... read more
Source: PubMedPublished on 2019-05-17