Can GBA1-Associated Parkinson Disease Be Modeled in the Mouse?

Can GBA1-Associated Parkinson Disease Be Modeled in the Mouse?
Can GBA1-Associated Parkinson Disease Be Modeled in the Mouse? Trends Neurosci. 2019 Jul 06;: Authors: Farfel-Becker T, Do J, Tayebi N, Sidransky E Abstract Homozygous and heterozygous mutations in GBA1, the gene implicated in Gaucher disease, increase the risk and severity of Parkinson disease (PD). We evaluated the design, phenotype, strengths, and limitations of current GBA1-associated PD mouse models. Although ... read more
Source: PubMedPublished on 2019-07-11