Causal effect of gut microbiota-derived metabolite trimethylamine N-oxide on Parkinson’s disease: A Mendelian randomisation study

Causal effect of gut microbiota-derived metabolite trimethylamine N-oxide on Parkinson’s disease: A Mendelian randomisation study
Eur J Neurol. 2023 Jan 24. doi: 10.1111/ene.15702. Online ahead of print.ABSTRACTBACKGROUND: It has been suggested that trimethylamine N-oxide (TMAO) is related to Parkinson's disease (PD) in observational studies. However, the direction of this association is inconsistent. An exploratory Mendelian randomisation study was conducted to investigate whether TMAO and its precursors have a causal relationship with PD.METHODS: We obtained summary ... read more
Source: PubMedPublished on 2023-01-24By Hang Zhou