Chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapy

Chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapy
Mol Cell Biochem. 2023 Jan 25. doi: 10.1007/s11010-022-04640-9. Online ahead of print.ABSTRACTChaperone-mediated autophagy (CMA) is the selective degradation process of intracellular components by lysosomes, which is required for the degradation of aggregate-prone proteins and contributes to proteostasis maintenance. Proteostasis is essential for normal cell function and survival, and it is determined by the balance of protein synthesis and degradation. Because ... read more
Source: PubMedPublished on 2023-01-25By Yi Liu