Chronic acrylamide exposure resulted in dopaminergic neuron loss, neuroinflammation and motor impairment in rats

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• Chronic acrylamide exposure resulted in dopaminergic neuron loss, neuroinflammation and motor impairment in rats August 2, 2022 Toxicol Appl Pharmacol. 2022 Jul 30:116190. doi: 10.1016/j.taap.2022.116190. Online ahead of print.ABSTRACTAcrylamide (ACR) as a by-product of Maillard reaction is widely present in food. Although ACR is known to exhibit neurotoxicity, most studies about ACR neurotoxicity are currently short-term high-dose providing limited reference value for human exposure. The present study aims to determine the effects of chronic ACR exposure on…
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