Chronic acrylamide exposure resulted in dopaminergic neuron loss, neuroinflammation and motor impairment in rats

Chronic acrylamide exposure resulted in dopaminergic neuron loss, neuroinflammation and motor impairment in rats
Toxicol Appl Pharmacol. 2022 Jul 30:116190. doi: 10.1016/j.taap.2022.116190. Online ahead of print.ABSTRACTAcrylamide (ACR) as a by-product of Maillard reaction is widely present in food. Although ACR is known to exhibit neurotoxicity, most studies about ACR neurotoxicity are currently short-term high-dose providing limited reference value for human exposure. The present study aims to determine the effects of chronic ACR exposure on ... read more
Source: PubMedPublished on 2022-08-02By Ying Liu