Circular RNA hsa_circ_0004381 Promotes Neuronal Injury in Parkinson’s Disease Cell Model by miR-185-5p/RAC1 Axis

Circular RNA hsa_circ_0004381 Promotes Neuronal Injury in Parkinson’s Disease Cell Model by miR-185-5p/RAC1 Axis
Neurotox Res. 2022 Jun 20. doi: 10.1007/s12640-022-00525-3. Online ahead of print.ABSTRACTThe study aims to explore the molecular mechanism involved in Parkinson's disease (PD). Hsa_circ_0004381, microRNA-185-5p (miR-185-5p), and Rac family small GTPase 1 (RAC1) level were measured by real-time quantitative polymerase chain reaction (RT-qPCR). Furthermore, cell viability and apoptosis rate were assessed by Cell Counting Kit-8 (CCK-8) and flow cytometry assays, ... read more
Source: PubMedPublished on 2022-06-21By Hongying Zhang