Citicoline in Ophthalmological Neurodegenerative Disease: A Comprehensive Review

Citicoline in Ophthalmological Neurodegenerative Disease: A Comprehensive Review
Pharmaceuticals (Basel). 2021 Mar 20;14(3):281. doi: 10.3390/ph14030281.ABSTRACTCytidine 5'-diphosphocholine has been widely studied in systemic neurodegenerative diseases, like Alzheimer's disease, Parkinson's disease, and brain ischemia. The rationale for the use of citicoline in ophthalmological neurodegenerative diseases, including glaucoma, anterior ischemic optic neuropathy, and diabetic retinopathy, is founded on its multifactorial mechanism of action and the involvement in several metabolic pathways, including ... read more
Source: PubMedPublished on 2021-04-03By Francesco Oddone