Cough medicine and Parkinson’s disease | Advances – Parkinson’s Life

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• The road ahead: 2022 January 20, 2022 # # # # The first post at the start of each year on the SoPD website tries to provide an overview of where things are in the search for ‘disease modifying’ therapies for Parkinson’s.  It is an exercise in managing expectations as well as discussing what research events are scheduled for the next year so that we can keep…
• Cough as a neurological sign: What a clinician should know November 4, 2022 World J Crit Care Med. 2022 May 9;11(3):115-128. doi: 10.5492/wjccm.v11.i3.115. eCollection 2022 May 9.ABSTRACTCough is a common respiratory complaint driving patients to seek medical advice. Besides being a fundamental respiratory sign, it is also a crucial neurological sign. There are three main types of coughs: Reflex cough (type I), voluntary cough (type II), and evoked cough (type III). Cough is…
• Cough as a neurological sign: What a clinician should know November 4, 2022 World J Crit Care Med. 2022 May 9;11(3):115-128. doi: 10.5492/wjccm.v11.i3.115. eCollection 2022 May 9.ABSTRACTCough is a common respiratory complaint driving patients to seek medical advice. Besides being a fundamental respiratory sign, it is also a crucial neurological sign. There are three main types of coughs: Reflex cough (type I), voluntary cough (type II), and evoked cough (type III). Cough is…
• Cough as a neurological sign: What a clinician should know November 4, 2022 World J Crit Care Med. 2022 May 9;11(3):115-128. doi: 10.5492/wjccm.v11.i3.115. eCollection 2022 May 9.ABSTRACTCough is a common respiratory complaint driving patients to seek medical advice. Besides being a fundamental respiratory sign, it is also a crucial neurological sign. There are three main types of coughs: Reflex cough (type I), voluntary cough (type II), and evoked cough (type III). Cough is…
• Cough as a neurological sign: What a clinician should know November 4, 2022 World J Crit Care Med. 2022 May 9;11(3):115-128. doi: 10.5492/wjccm.v11.i3.115. eCollection 2022 May 9.ABSTRACTCough is a common respiratory complaint driving patients to seek medical advice. Besides being a fundamental respiratory sign, it is also a crucial neurological sign. There are three main types of coughs: Reflex cough (type I), voluntary cough (type II), and evoked cough (type III). Cough is…
• Cough as a neurological sign: What a clinician should know November 4, 2022 World J Crit Care Med. 2022 May 9;11(3):115-128. doi: 10.5492/wjccm.v11.i3.115. eCollection 2022 May 9.ABSTRACTCough is a common respiratory complaint driving patients to seek medical advice. Besides being a fundamental respiratory sign, it is also a crucial neurological sign. There are three main types of coughs: Reflex cough (type I), voluntary cough (type II), and evoked cough (type III). Cough is…
• Immediate Effects of Sensorimotor Training in Airway Protection (smTAP) on Cough Outcomes in Progressive Supranuclear Palsy: A Feasibility Study. January 31, 2021 Related ArticlesImmediate Effects of Sensorimotor Training in Airway Protection (smTAP) on Cough Outcomes in Progressive Supranuclear Palsy: A Feasibility Study. Dysphagia. 2021 Jan 30;: Authors: Borders JC, Curtis JA, Sevitz JS, Vanegas-Arroyave N, Troche MS Abstract Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by a high prevalence of dysphagia, cough dysfunction, and resultant aspiration pneumonia. Sensorimotor cough function…
• The road ahead: 2021 January 25, 2021 # # # # At the start of each year, it is a useful practise to layout what is planned over the next 12 months. The events that are scheduled for the year to come, so that we can keep an eye out for them. Obviously, where 2021 will end actually is unpredictable, but an outline of what is scheduled…
• Sensorimotor Cough Dysfunction Is Prevalent and Pervasive in Progressive Supranuclear Palsy June 26, 2021 Mov Disord. 2021 Jun 26. doi: 10.1002/mds.28707. Online ahead of print.ABSTRACTBACKGROUND: Pneumonia, a leading cause of death in progressive supranuclear palsy (PSP), results from progressive and pervasive deficits of airway protection, including both cough and swallowing dysfunction. Cough protects the airway by expelling aspirate and may be an important therapeutic target to protect against pneumonia in the presence of dysphagia.…
• Sensorimotor Cough Dysfunction Is Prevalent and Pervasive in Progressive Supranuclear Palsy June 26, 2021 Mov Disord. 2021 Jun 26. doi: 10.1002/mds.28707. Online ahead of print.ABSTRACTBACKGROUND: Pneumonia, a leading cause of death in progressive supranuclear palsy (PSP), results from progressive and pervasive deficits of airway protection, including both cough and swallowing dysfunction. Cough protects the airway by expelling aspirate and may be an important therapeutic target to protect against pneumonia in the presence of dysphagia.…
• Sensorimotor Cough Dysfunction Is Prevalent and Pervasive in Progressive Supranuclear Palsy June 26, 2021 Mov Disord. 2021 Jun 26. doi: 10.1002/mds.28707. Online ahead of print.ABSTRACTBACKGROUND: Pneumonia, a leading cause of death in progressive supranuclear palsy (PSP), results from progressive and pervasive deficits of airway protection, including both cough and swallowing dysfunction. Cough protects the airway by expelling aspirate and may be an important therapeutic target to protect against pneumonia in the presence of dysphagia.…
• Sensorimotor Cough Dysfunction Is Prevalent and Pervasive in Progressive Supranuclear Palsy June 26, 2021 Mov Disord. 2021 Jun 26. doi: 10.1002/mds.28707. Online ahead of print.ABSTRACTBACKGROUND: Pneumonia, a leading cause of death in progressive supranuclear palsy (PSP), results from progressive and pervasive deficits of airway protection, including both cough and swallowing dysfunction. Cough protects the airway by expelling aspirate and may be an important therapeutic target to protect against pneumonia in the presence of dysphagia.…
• Dual Tasking Influences Cough Reflex Outcomes in Adults with Parkinson's Disease: A Controlled Study. January 4, 2021 Related ArticlesDual Tasking Influences Cough Reflex Outcomes in Adults with Parkinson's Disease: A Controlled Study. Dysphagia. 2021 Jan 02;: Authors: Perry SE, Troche MS Abstract Coughing is an essential airway protective reflex. In healthy young adults, cough somatosensation changes when attention is divided (dual tasking). Whether the same is true in populations at risk of aspiration remains unknown. We present…
• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
• Monthly Research Review – February 2021 February 28, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during February 2021. The post is divided into eight parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news…
• A New Therapeutic Approach for Dystussia and Atussia in Neurogenic Dysphagia: Effect of Aerosolized Capsaicin on Peak Cough Flow April 17, 2022 Dysphagia. 2022 Apr 16. doi: 10.1007/s00455-022-10439-z. Online ahead of print.ABSTRACTSwallowing and cough are crucial components of airway protection. In patients with neurogenic dysphagia (ND), there is a high prevalence of dystussia (impaired cough) and atussia (absence of cough). As a result, the ability to detect and remove aspirated material from the airway decreases, exacerbating the sequelae associated with ND, including…
• A New Therapeutic Approach for Dystussia and Atussia in Neurogenic Dysphagia: Effect of Aerosolized Capsaicin on Peak Cough Flow April 17, 2022 Dysphagia. 2022 Apr 16. doi: 10.1007/s00455-022-10439-z. Online ahead of print.ABSTRACTSwallowing and cough are crucial components of airway protection. In patients with neurogenic dysphagia (ND), there is a high prevalence of dystussia (impaired cough) and atussia (absence of cough). As a result, the ability to detect and remove aspirated material from the airway decreases, exacerbating the sequelae associated with ND, including…
• A New Therapeutic Approach for Dystussia and Atussia in Neurogenic Dysphagia: Effect of Aerosolized Capsaicin on Peak Cough Flow April 17, 2022 Dysphagia. 2022 Apr 16. doi: 10.1007/s00455-022-10439-z. Online ahead of print.ABSTRACTSwallowing and cough are crucial components of airway protection. In patients with neurogenic dysphagia (ND), there is a high prevalence of dystussia (impaired cough) and atussia (absence of cough). As a result, the ability to detect and remove aspirated material from the airway decreases, exacerbating the sequelae associated with ND, including…
• A New Therapeutic Approach for Dystussia and Atussia in Neurogenic Dysphagia: Effect of Aerosolized Capsaicin on Peak Cough Flow April 17, 2022 Dysphagia. 2022 Apr 16. doi: 10.1007/s00455-022-10439-z. Online ahead of print.ABSTRACTSwallowing and cough are crucial components of airway protection. In patients with neurogenic dysphagia (ND), there is a high prevalence of dystussia (impaired cough) and atussia (absence of cough). As a result, the ability to detect and remove aspirated material from the airway decreases, exacerbating the sequelae associated with ND, including…
• A New Therapeutic Approach for Dystussia and Atussia in Neurogenic Dysphagia: Effect of Aerosolized Capsaicin on Peak Cough Flow April 17, 2022 Dysphagia. 2022 Apr 16. doi: 10.1007/s00455-022-10439-z. Online ahead of print.ABSTRACTSwallowing and cough are crucial components of airway protection. In patients with neurogenic dysphagia (ND), there is a high prevalence of dystussia (impaired cough) and atussia (absence of cough). As a result, the ability to detect and remove aspirated material from the airway decreases, exacerbating the sequelae associated with ND, including…
• Six Pillars of Parkinson’s December 11, 2022 “In all human affairs there are efforts, and there are results, and the strength of the effort is the measure of the result.” James Allen “Storms make trees take deeper roots.” Dolly Parton NOTE ADDED IN PROOF: Earlier today, I inadvertently published this post’s unfinished and unproofed version. It was titled “6 Pillars of Parkinson’s.” I apologize for pushing the…
• Monthly research review – March 2021 March 31, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during March 2021. The post is divided into ten parts based on the type of research: Top 5 pieces of Parkinson’s news Articles of general interest Basic biology…