Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential

Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential
Commun Biol. 2022 Nov 22;5(1):1279. doi: 10.1038/s42003-022-03965-x.ABSTRACTDementia with Lewy bodies (DLB) is a common form of dementia with known genetic and environmental interactions. However, the underlying epigenetic mechanisms which reflect these gene-environment interactions are poorly studied. Herein, we measure genome-wide DNA methylation profiles of post-mortem brain tissue (Broadmann area 7) from 15 pathologically confirmed DLB brains and compare them with ... read more
Source: PubMedPublished on 2022-11-23By Xiaojian Shao