Development of an extended half-life GM-CSF fusion protein for Parkinson’s disease

Development of an extended half-life GM-CSF fusion protein for Parkinson’s disease
J Control Release. 2022 Jun 20:S0168-3659(22)00353-4. doi: 10.1016/j.jconrel.2022.06.024. Online ahead of print.ABSTRACTTransformation of CD4+ T cell effector to regulatory (Teff to Treg) cells have been shown to attenuate disease progression by restoring immunological balance during the onset and progression of neurodegenerative diseases. In our prior studies, we defined a safe and effective pathway to restore this balance by restoring Treg ... read more
Source: PubMedPublished on 2022-06-23By Pravin Yeapuri