Distribution, Function, and Expression of the Apelinergic System in the Healthy and Diseased Mammalian Brain

Distribution, Function, and Expression of the Apelinergic System in the Healthy and Diseased Mammalian Brain
Genes (Basel). 2022 Nov 21;13(11):2172. doi: 10.3390/genes13112172.ABSTRACTApelin, a peptide initially isolated from bovine stomach extract, is an endogenous ligand for the Apelin Receptor (APLNR). Subsequently, a second peptide, ELABELA, that can bind to the receptor has been identified. The Apelin receptor and its endogenous ligands are widely distributed in mammalian organs. A growing body of evidence suggests that this system ... read more
Source: PubMedPublished on 2022-11-24By Martin N Ivanov