DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression

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• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
• DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression March 18, 2023 J Affect Disord. 2023 Mar 16:S0165-0327(23)00359-2. doi: 10.1016/j.jad.2023.03.031. Online ahead of print.ABSTRACTBACKGROUND: The FKBP5 and NR3C1 genes play an important role in stress response, thus impacting mental health. Stress factor exposure in early life, such as maternal depression, may contribute to epigenetic modifications in stress response genes, increasing the susceptibility to different psychopathologies. The present study aimed to evaluate the…
• DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression March 18, 2023 J Affect Disord. 2023 Mar 16:S0165-0327(23)00359-2. doi: 10.1016/j.jad.2023.03.031. Online ahead of print.ABSTRACTBACKGROUND: The FKBP5 and NR3C1 genes play an important role in stress response, thus impacting mental health. Stress factor exposure in early life, such as maternal depression, may contribute to epigenetic modifications in stress response genes, increasing the susceptibility to different psychopathologies. The present study aimed to evaluate the…
• DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression March 18, 2023 J Affect Disord. 2023 Mar 16:S0165-0327(23)00359-2. doi: 10.1016/j.jad.2023.03.031. Online ahead of print.ABSTRACTBACKGROUND: The FKBP5 and NR3C1 genes play an important role in stress response, thus impacting mental health. Stress factor exposure in early life, such as maternal depression, may contribute to epigenetic modifications in stress response genes, increasing the susceptibility to different psychopathologies. The present study aimed to evaluate the…
• DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression March 18, 2023 J Affect Disord. 2023 Mar 16:S0165-0327(23)00359-2. doi: 10.1016/j.jad.2023.03.031. Online ahead of print.ABSTRACTBACKGROUND: The FKBP5 and NR3C1 genes play an important role in stress response, thus impacting mental health. Stress factor exposure in early life, such as maternal depression, may contribute to epigenetic modifications in stress response genes, increasing the susceptibility to different psychopathologies. The present study aimed to evaluate the…
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