Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair

Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair
J Parkinsons Dis. 2021 Mar 29. doi: 10.3233/JPD-212609. Online ahead of print.ABSTRACTCell therapy for Parkinson's disease (PD) is aimed to replace the degenerated midbrain dopamine (mDA) neurons and restore DA neurotransmission in the denervated forebrain targets. A limitation of the intrastriatal grafting approach, which is currently used in clinical trials, is that the mDA neurons are implanted into the target ... read more
Source: PubMedPublished on 2021-04-05By Anders Björklund