Down-regulated long non-coding RNA RMST ameliorates dopaminergic neuron damage in Parkinson’s disease rats via regulation of TLR/NF-kappaB signaling pathway

Down-regulated long non-coding RNA RMST ameliorates dopaminergic neuron damage in Parkinson’s disease rats via regulation of TLR/NF-kappaB signaling pathway
Brain Res Bull. 2021 Apr 29:S0361-9230(21)00129-5. doi: 10.1016/j.brainresbull.2021.04.026. Online ahead of print.ABSTRACTOBJECTIVE: Current treatment and prognosis of Parkinson's disease (PD) are not ideal. This study explored the mechanism of long non-coding RNA (lncRNA) rhabdomyosarcoma 2-associated transcript (RMST) in dopaminergic (DA) neuron damage in PD rats.METHODS: PD rats were modeled and injected with RMST silence or overexpression vectors to figure out ... read more
Source: PubMedPublished on 2021-05-02By Xuelian Ma