Elongated nanoporous Au networks improve somatic cell direct conversion into induced dopaminergic neurons for Parkinson’s disease therapy

Elongated nanoporous Au networks improve somatic cell direct conversion into induced dopaminergic neurons for Parkinson’s disease therapy
Acta Biomater. 2022 Aug 2:S1742-7061(22)00460-3. doi: 10.1016/j.actbio.2022.07.058. Online ahead of print.ABSTRACTThe efficient production of dopaminergic neurons via the direct conversion of other cell types is of interest as a potential therapeutic approach for Parkinson's disease. This study aimed to investigate the use of elongated porous gold nanorods (AuNpRs) as an enhancer of cell fate conversion. We observed that AuNpRs promoted ... read more
Source: PubMedPublished on 2022-08-05By Sungwoo Lee