Epigenetic Clock Acceleration Is Linked to Age at Onset of Parkinson’s Disease

Epigenetic Clock Acceleration Is Linked to Age at Onset of Parkinson’s Disease
Mov Disord. 2022 Aug 3. doi: 10.1002/mds.29157. Online ahead of print.ABSTRACTBACKGROUND: Aging is the strongest risk factor for Parkinson's disease (PD), which is a clinically heterogeneous movement disorder with highly variable age at onset. DNA methylation age (DNAm age) is an epigenetic clock that could reflect biological aging.OBJECTIVES: The aim was to evaluate whether PD age at onset is associated ... read more
Source: PubMedPublished on 2022-08-03By Xuelin Tang