Epimedin B exerts neuroprotective effect against MPTP-induced mouse model of Parkinson’s disease: GPER as a potential target

Epimedin B exerts neuroprotective effect against MPTP-induced mouse model of Parkinson’s disease: GPER as a potential target
Biomed Pharmacother. 2022 Dec;156:113955. doi: 10.1016/j.biopha.2022.113955. Epub 2022 Nov 4.ABSTRACTMitochondrial dysfunction and oxidative stress play important roles in the neuropathogenesis of Parkinson's disease (PD). Epimedin B, the second highest active ingredient in the flavonoids of Herba Epimedii, has been proven effective in treating osteoporosis and oxaliplatin-induced peripheral neuropathy. The present study aims to investigate the neuroprotective effects of Epimedin B ... read more
Source: PubMedPublished on 2022-11-22By Mei Zhang