Evaluating white matter alterations in Parkinson’s disease-related parkin S/N167 mutation carriers using tract-based spatial statistics

Evaluating white matter alterations in Parkinson’s disease-related parkin S/N167 mutation carriers using tract-based spatial statistics
Quant Imaging Med Surg. 2022 Aug;12(8):4272-4285. doi: 10.21037/qims-21-1007.ABSTRACTBACKGROUND: Genetic susceptibility plays an important role in the pathogenesis of Parkinson's disease (PD). parkin S/N167 mutations may increase the risk of PD and affect white matter fibers in the brain. This cross-sectional study explored the effects of gene polymorphisms on white matter fiber damage in PD.METHODS: In all, 54 cases were enrolled ... read more
Source: PubMedPublished on 2022-08-03By Jinqiu Yu