Exploring the Epigenetic Regulated Modulation of Fibroblast Growth Factor 21 Involvement in High-Fat Diet Associated Parkinson’s Disease in Rats

Exploring the Epigenetic Regulated Modulation of Fibroblast Growth Factor 21 Involvement in High-Fat Diet Associated Parkinson’s Disease in Rats
ACS Chem Neurosci. 2023 Jan 24. doi: 10.1021/acschemneuro.2c00659. Online ahead of print.ABSTRACTImbalance in brain glucose metabolism and epigenetic modulation during the disease course of insulin resistance (IR) associated with Parkinson's disease (PD) risk remains a prime concern. Fibroblast growth factor 21 (FGF21), the metabolic hormone, improves insulin sensitivity and elicits anti-diabetic properties. Chronic stress during brain IR may modulate the ... read more
Source: PubMedPublished on 2023-01-25By Violina Kakoty