Exposure to PM2.5 aggravates Parkinson’s disease via inhibition of autophagy and mitophagy pathway

Exposure to PM2.5 aggravates Parkinson’s disease via inhibition of autophagy and mitophagy pathway
Toxicology. 2021 Apr 3:152770. doi: 10.1016/j.tox.2021.152770. Online ahead of print.ABSTRACTExtensive health studies had declared that exposure to particulate matter (PM) was closely associated with neurodegenerative diseases, i.e. Parkinson's disease (PD). Our aim was to clarify the potential molecular mechanism by which PM2.5 aggravated PD symptoms using in vitro and in vivo PD models. In this study, PC12 cells treated with ... read more
Source: PubMedPublished on 2021-04-06By Yueqi Wang