Fluorescent Probe for Selective Imaging of α-Synuclein Fibrils in Living Cells

Fluorescent Probe for Selective Imaging of α-Synuclein Fibrils in Living Cells
ACS Chem Neurosci. 2021 Apr 5. doi: 10.1021/acschemneuro.1c00090. Online ahead of print.ABSTRACTPlaques of amyloid fibrils composed of neuronal protein α-synuclein are one of the hallmarks of Parkinson's disease, and their selective imaging is crucial to study the mechanism of its pathogenesis. However, the existing fluorescent probes for amyloids are efficient only in solution and tissue systems, and they are not ... read more
Source: PubMedPublished on 2021-04-05By Pankaj Gaur