Focused Ultrasound Improves Parkinson’s Patients’ Movement – Technology Networks

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• The road ahead: 2022 January 20, 2022 # # # # The first post at the start of each year on the SoPD website tries to provide an overview of where things are in the search for ‘disease modifying’ therapies for Parkinson’s.  It is an exercise in managing expectations as well as discussing what research events are scheduled for the next year so that we can keep…
• The road ahead: 2021 January 25, 2021 # # # # At the start of each year, it is a useful practise to layout what is planned over the next 12 months. The events that are scheduled for the year to come, so that we can keep an eye out for them. Obviously, where 2021 will end actually is unpredictable, but an outline of what is scheduled…
• June 2, 2019 - Parkinson's Weekly Update June 1, 2019 Weekly Update - Highlights include: World Parkinson Congress 2019 heads to Kyoto, Japan for the epic battle of "Parkinson's Disease vs. Chopsticks - Will We Go Home Hungry?"; focused ultrasound and PD; NIH awards $3 million grant for 5-year PD exercise study; deteriorating financial skills, dementia and brain plaques; hockey pucks for Parkinson's; inspiring people with PD; how DBS changes…
• Focused Ultrasound in Parkinson’s: A Conversation With Arjun Desai, MD April 7, 2022 Last November, the U.S. Food and Drug Administration approved Exablate Neuro to treat motor symptoms in Parkinson’s disease patients, as reported by Parkinson’s News Today‘s Patricia Inacio, PhD. Created by medical device company Insightec, Exablate Neuro is a magnetic resonance, image-guided, focused ultrasound (MRgFUS) system that can treat tremors noninvasively. As clinical trials continue, the technology is gaining momentum. I…
• Brief Report: Pallidothalamic Tractotomy by Focused Ultrasound for Parkinson’s Disease March 3, 2023 “Patience and fortitude conquer all things.” Ralph Waldo Emerson “I know of no higher fortitude than stubborness in the face of overwhelming odds.” Louis Nizer Overview: Recently, I reviewed a clinical trial involving ablation of the globus pallidus by focused ultrasound to treat Parkinson’s (click here to read this blog post). Some time ago, I was asked my opinion about…
• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
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• Ultrasound-activated Neurons Used to Study Parkinson’s, Other Neurodegenerative Diseases March 18, 2020 Using an engineered sound-sensitive protein, researchers have developed neurons that can be activated by ultrasound. This could be useful in studying, and even developing therapies for, neurological diseases, including Parkinson’s. The study, “Sonogenetic Modulation of Cellular Activities Using an Engineered Auditory-Sensing Protein,” was published in Nano Letters. The ability to control neuronal activity in a non-invasive manner is useful for basic…
• Focused Ultrasound Ablation Therapy of the Globus Pallidus for Parkinson’s February 28, 2023 “Be brave. Take risks. Nothing can substitute experience.” Paulo Coelho “Resilience is not what happens to you. It’s how you react to, respond to, and recover from what happens to you.” Jeffrey Gitomer Introduction: The clinical trial results were published in the New England Journal of Medicine by Krishna et al. (2023), dealing with ultrasound treatment of the globus pallidus internus…
• Breathtaking research April 24, 2022 # # # # Breathing is one of those many aspects of life that we all take completely for granted for the vast majority of our time on planet Earth. It represents not only a magnificent means of providing our bodies with oxygen, but also disposing of waste. Recently researchers have attempted to see if there are any components in…
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• Monitoring an Apple in motion June 16, 2021 # # # # Wearable technology offers the potential to more accurately monitor the symptoms of Parkinson’s in real time. Such information could allow for better and more precise management of the condition, as well as providing objective measures for clinical trials exploring novel therapies. Assessing some of the features of Parkinson’s, however, is not easy. Differentiating jerky involuntary movements…
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• The Heart of Research: One Volunteer’s Experience as Part of a Clinical Trial October 20, 2021 At the heart of the clinical studies carried out by researchers seeking better treatments or a cure for Parkinson’s, are the volunteers, ordinary people just like you, helping to advance the science and potentially improving or even saving lives in the decades to come through their participation. Susan Fullerton is one of those brave volunteers. She chose to participate in…
• Monthly Research Review – February 2021 February 28, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during February 2021. The post is divided into eight parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news…
• Parkinson’s Questions on Tremor, Prognosis, & Progression Answered February 14, 2023 Your Questions Answered on Tremor, Prognosis & More On a recent episode of APDA’s Dr. Gilbert Hosts, Dr. Drew Falconer joined me to answer your questions about Parkinson’s disease (PD). We covered a lot of ground during the broadcast and answered many questions from the audience. It was a very informative conversation, and we encourage you to watch the full broadcast of…
• Mapping Knowledge Structure and Research Frontiers of Ultrasound-Induced Blood-Brain Barrier Opening: A Scientometric Study August 2, 2021 Front Neurosci. 2021 Jul 14;15:706105. doi: 10.3389/fnins.2021.706105. eCollection 2021.ABSTRACTBackground: Among the effective approaches developed for blood-brain barrier (BBB) opening, ultrasound is recognized as a non-invasive technique that can induce localized BBB opening transiently and repeatedly. This technique has aroused broad attention from researchers worldwide, and numerous articles have been published recently. However, no existing study has systematically examined this field…
• Mapping Knowledge Structure and Research Frontiers of Ultrasound-Induced Blood-Brain Barrier Opening: A Scientometric Study August 2, 2021 Front Neurosci. 2021 Jul 14;15:706105. doi: 10.3389/fnins.2021.706105. eCollection 2021.ABSTRACTBackground: Among the effective approaches developed for blood-brain barrier (BBB) opening, ultrasound is recognized as a non-invasive technique that can induce localized BBB opening transiently and repeatedly. This technique has aroused broad attention from researchers worldwide, and numerous articles have been published recently. However, no existing study has systematically examined this field…
• Mapping Knowledge Structure and Research Frontiers of Ultrasound-Induced Blood-Brain Barrier Opening: A Scientometric Study August 2, 2021 Front Neurosci. 2021 Jul 14;15:706105. doi: 10.3389/fnins.2021.706105. eCollection 2021.ABSTRACTBackground: Among the effective approaches developed for blood-brain barrier (BBB) opening, ultrasound is recognized as a non-invasive technique that can induce localized BBB opening transiently and repeatedly. This technique has aroused broad attention from researchers worldwide, and numerous articles have been published recently. However, no existing study has systematically examined this field…
• Mapping Knowledge Structure and Research Frontiers of Ultrasound-Induced Blood-Brain Barrier Opening: A Scientometric Study August 2, 2021 Front Neurosci. 2021 Jul 14;15:706105. doi: 10.3389/fnins.2021.706105. eCollection 2021.ABSTRACTBackground: Among the effective approaches developed for blood-brain barrier (BBB) opening, ultrasound is recognized as a non-invasive technique that can induce localized BBB opening transiently and repeatedly. This technique has aroused broad attention from researchers worldwide, and numerous articles have been published recently. However, no existing study has systematically examined this field…