Foundations of Magnetic Resonance-Guided Focused Ultrasonography.

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• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
• Monthly Research Review – December 2020 December 31, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during December 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Conferences/lectures Other news…
• Monthly research review: February 2020 February 29, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during February 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Other news Review…
• 2019: Year in review December 31, 2019   In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2019. Month-by-month we will briefly discuss some of the major pieces of research/announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies to any researchers who…
• DBS: location, location, location December 15, 2019   Deep brain stimulation (or DBS) represents a well established treatment option for individuals with Parkinson’s who no longer respond to standard therapies. It involves tiny electrodes being embedded in the brain and they modulate populations of neurons that have become dysfunctional. The results of the DBS procedure can be “miraculous” for some individuals – reducing tremors and significantly improving…
• 2020: Year in Review January 1, 2021 # # # # In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2020. Month-by-month we will briefly discuss some of the major pieces of research/ announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies…
• Shining a light on Parkinson’s November 7, 2019   NOTE: The information in today’s post should not be considered an endorsement of PhotoPharmics or the treatment they are proposing. The author of this blog has had no communication with the company. The information in this post is provided because the author has been asked by readers to discuss it. In October 2018, at the annual International Movement Disorders…
• Monthly Research Review – November 2020 November 30, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during November 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Conferences/lectures Other news…
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• Monthly Research Review – September 2019 September 30, 2019   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during September 2019. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Other news Review…
• A Primer on Pain and Parkinson’s September 21, 2020 Introduction Studies show that between 60 and 83% of people with Parkinson’s report experiencing pain, and chronic pain is twice as common in people living with Parkinson’s than it is in those without Parkinson’s. Several different types of pain are associated with Parkinson’s, and effective management requires coordination with your care team and implementation of pharma- and non-pharmacological treatments. In…
• Monthly Research Review: Jaunary 2020 January 31, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during January 2020. The post is divided into seven parts based on the type of research: Basic biology, Disease mechanism, Clinical research, New clinical trials, Clinical trial news, Other news, and…
• Monthly Research Review – November 2019 November 30, 2019   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during November 2019. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Other news Review…
• Bayer doubles down on Parkinson’s? December 10, 2020 # # # # News today of two biotech companies merging did not cause much of a ripple in the media, but the wider implications of the move are rather significant for Parkinson’s. Today it was announced that Brain Neurotherapy Bio (BNB) is going to merge with Asklepios Biopharmaceutical (aka AskBio). BNB are currently clinically testing a GDNF gene therapy…
• PARP-kinson’s goes chlorogenic December 20, 2020 # # # # For a long time it was been reported that coffee may be able to reduce the risk of developing Parkinson’s, but the mechansim by which this association could be occurring has remained elusive. Now researchers from South Korea have discovered a biological pathway that could help to explain the protective association. It involves a protein called…
• Innovative Applications of MR-Guided Focused Ultrasound for Neurological Disorders. December 23, 2020 Related ArticlesInnovative Applications of MR-Guided Focused Ultrasound for Neurological Disorders. World Neurosurg. 2021 Jan;145:581-589 Authors: Stavarache MA, Chazen JL, Kaplitt MG Abstract Magnetic resonance-guided focused ultrasound (MRgFUS) is a cutting-edge technology that is changing the practice of movement disorders surgery. Given the noninvasive and innovative nature of this technology, there is great interest in expanding the use of MRgFUS to…
• Monthly research review – October 2019 October 31, 2019   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during October 2019. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Other news Review…
• Is Pain a Symptom of Parkinson’s Disease? August 27, 2019 Pain is a common but overlooked problem in Parkinson’s disease. Pain is an often overlooked non-motor symptom of Parkinson’s disease (PD). Studies show that between 40-80% of people with PD report pain, which is likely why it is often suggested as a topic for this blog. (Please feel free to suggest a topic for future blog posts.) One of the…
• Milestones in Parkinson’s Disease Research and Discovery April 11, 2017 “The real voyage of discovery consists not in seeking new landscapes, but in having new eyes.” Marcel Proust “The process of scientific discovery is, in effect, a continual flight from wonder.” Albert Einstein Preface:  Happy birthday to James Parkinson (neurologist, geologist, scientist, activist),  born April 11, 1755 and died December 21, 1824.  World Parkinson’s Day April 11, 2017. Introduction to…
• ReWriting the World February 16, 2020 The following is an expanded version of a piece that recently appeared in Times Higher Education. It was written with Prof. Hilal A. Lashuel, the director of the laboratory of molecular and chemical biology of neurodegeneration at the Swiss Federal Institute of Technology Lausanne (École Polytechnique Federale de Lausanne, EPFL).     “That’s it, that’s the cure.” I stood squinting at…
• ReWriting the World February 16, 2020 The following is an expanded version of a piece that recently appeared in Times Higher Education. It was written with Prof. Hilal A. Lashuel, the director of the laboratory of molecular and chemical biology of neurodegeneration at the Swiss Federal Institute of Technology Lausanne (École Polytechnique Federale de Lausanne, EPFL).     “That’s it, that’s the cure.” I stood squinting at…
• ReWriting the World February 16, 2020 The following is an expanded version of a piece that recently appeared in Times Higher Education. It was written with Prof. Hilal A. Lashuel, the director of the laboratory of molecular and chemical biology of neurodegeneration at the Swiss Federal Institute of Technology Lausanne (École Polytechnique Federale de Lausanne, EPFL).     “That’s it, that’s the cure.” I stood squinting at…