Functional analysis of distinct populations of subthalamic nucleus neurons on Parkinson’s disease and OCD-like behaviors in mice

Functional analysis of distinct populations of subthalamic nucleus neurons on Parkinson’s disease and OCD-like behaviors in mice
Mol Psychiatry. 2021 Jun 7. doi: 10.1038/s41380-021-01162-6. Online ahead of print.ABSTRACTThe subthalamic nucleus (STN) is a component of the basal ganglia and plays a key role to control movement and limbic-associative functions. STN modulation with deep brain stimulation (DBS) improves the symptoms of Parkinson's disease (PD) and obsessive-compulsive disorder (OCD) patients. However, DBS does not allow for cell-type-specific modulation of ... read more
Source: PubMedPublished on 2021-06-08By Luca Parolari