G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses.

G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses.
Related ArticlesG2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses. Anim Cells Syst (Seoul). 2019 Apr;23(2):106-111 Authors: Ho DH, Lee H, Son I, Seol W Abstract Leucine rich-repeat kinase 2 (LRRK2) is involved in the pathogenesis of Parkinson's disease (PD). LRRK2 has kinase and GTPase activities, and mediates several cell functions, including vesicle trafficking, apoptosis, autophagy, mitochondrial dynamics, and ... read more
Source: PubMedPublished on 2019-04-06