Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies

Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies
J Parkinsons Dis. 2021 Jun 4. doi: 10.3233/JPD-212679. Online ahead of print.ABSTRACTThe protein alpha-Synuclein (α-Syn) is a key contributor to the etiology of Parkinson's disease (PD) with aggregation, trans-neuronal spread, and/or depletion of α-Syn being viewed as crucial events in the molecular processes that results in neurodegeneration. The exact succession of pathological occurrences that lead to neuronal death are still ... read more
Source: PubMedPublished on 2021-06-07By Ivette M Sandoval