Genetic modifiers of age-at-onset in polyglutamine diseases.

Genetic modifiers of age-at-onset in polyglutamine diseases.
Related ArticlesGenetic modifiers of age-at-onset in polyglutamine diseases. Ageing Res Rev. 2018 Dec;48:99-108 Authors: Chen Z, Sequeiros J, Tang B, Jiang H Abstract Polyglutamine (polyQ) diseases are a group of clinically and genetically heterogeneous neurodegenerative diseases. Expansion size correlates with age-at-onset (AO) and severity, and shows a critical threshold for each polyQ disease. Although an expanded CAG tract is ... read more
Source: PubMedPublished on 2019-07-30