Genetic testing for Parkinson’s disease in clinical practice

Genetic testing for Parkinson’s disease in clinical practice
J Neural Transm (Vienna). 2023 Mar 16. doi: 10.1007/s00702-023-02612-x. Online ahead of print.ABSTRACTThe identification of disease-causing mutations or strong risk factors for Parkinson's disease in genes encoding proteins such as α-synuclein (SNCA), leucine-rich repeat kinase-2 (LRRK2), or glucocerebrosidase (GBA1) has led to a better understanding of the different components of disease pathogenesis. Many gene and mutation-specific targeted disease-modifying treatments are ... read more
Source: PubMedPublished on 2023-03-17By Thomas Gasser