Genetics of validated Parkinson’s disease subtypes in the Oxford Discovery and Tracking Parkinson’s cohorts

Genetics of validated Parkinson’s disease subtypes in the Oxford Discovery and Tracking Parkinson’s cohorts
J Neurol Neurosurg Psychiatry. 2022 Jun 22:jnnp-2021-327376. doi: 10.1136/jnnp-2021-327376. Online ahead of print.ABSTRACTOBJECTIVES: To explore the genetics of four Parkinson's disease (PD) subtypes that have been previously described in two large cohorts of patients with recently diagnosed PD. These subtypes came from a data-driven cluster analysis of phenotypic variables.METHODS: We looked at the frequency of genetic mutations in glucocerebrosidase (GBA) ... read more
Source: PubMedPublished on 2022-06-22By Michael Lawton