Granulocyte-colony stimulating factor, a potential candidate for the treatment of Parkinson’s disease

Granulocyte-colony stimulating factor, a potential candidate for the treatment of Parkinson’s disease
J Neurosurg Sci. 2021 May 3. doi: 10.23736/S0390-5616.21.05314-5. Online ahead of print.ABSTRACTBACKGROUND: Granulocyte colony-stimulating factor (G-CSF) activates the PI3K/Akt pathway to exert neuroprotective effects. The current study aimed to determine if G-CSF reverses behavioral deficits, even after motor malfunction occurs in Paraquat (PQ)-treated mice.METHODS: Male C57BL/6 mice (8 weeks old) were divided into 3 groups: PQ + G-CSF-treated group (n=8); ... read more
Source: PubMedPublished on 2021-05-04By Jiawen Yuan