Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome

Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome
Bioeng Transl Med. 2022 Nov 23;8(2):e10455. doi: 10.1002/btm2.10455. eCollection 2023 Mar.ABSTRACTThe intestinal flora has become very active in studies related to Parkinson's disease (PD) in recent years. The microbe-gut-brain axis is closely related to the maintenance of brain homeostasis as well as PD pathogenesis. Alterations in gut bacteria can contribute to neuroinflammation and dopamine (DA) neurodegeneration. Lactobacillus murinus, a gram-positive ... read more
Source: PubMedPublished on 2023-03-17By Hong-Xia Fan