Helicobacter pylori eradication improves motor fluctuations in advanced Parkinson’s disease patients: A prospective cohort study (HP-PD trial)

Helicobacter pylori eradication improves motor fluctuations in advanced Parkinson’s disease patients: A prospective cohort study (HP-PD trial)
PLoS One. 2021 May 4;16(5):e0251042. doi: 10.1371/journal.pone.0251042. eCollection 2021.ABSTRACTBACKGROUND: Helicobacter pylori (HP) is a bacterium associated with many gastrointestinal (GI) diseases and has shown a high prevalence in Parkinson's disease (PD). As HP-associated GI dysfunction could affect L-dopa (levodopa) absorption, HP eradication might improve the clinical response and decrease motor fluctuations.METHODS: A prospective cohort study was conducted on the clinical ... read more
Source: PubMedPublished on 2021-05-04By Praween Lolekha