Increased blood-derived mitochondrial DNA copy number in African ancestry individuals with Parkinson’s disease

Increased blood-derived mitochondrial DNA copy number in African ancestry individuals with Parkinson’s disease
Parkinsonism Relat Disord. 2022 Jun 15;101:1-5. doi: 10.1016/j.parkreldis.2022.06.003. Online ahead of print.ABSTRACTINTRODUCTION: Altered levels of mitochondrial DNA copy number (mtDNA-CN) have been proposed as a proxy for mitochondrial dysfunction. Following reports of mtDNA depletion in the blood and substantia nigra of Parkinson's disease (PD) cases, mtDNA-CN was also suggested as a possible biomarker for PD. Therefore, this study aimed to ... read more
Source: PubMedPublished on 2022-06-21By Amica Corda Müller-Nedebock