Industrial Trichloroethylene Possibly Linked To Parkinson’s Disease – Kaiser Health News

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• The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease February 26, 2021 Neurobiol Dis. 2021 Feb 23:105312. doi: 10.1016/j.nbd.2021.105312. Online ahead of print.ABSTRACTGene-environment interaction is implicated in the majority of idiopathic Parkinson's disease (PD) risk, and some of the most widespread environmental contaminants are selectively toxic to dopaminergic neurons. Pesticides have long been connected to PD incidence, however, it has become increasingly apparent that other industrial byproducts likely influence neurodegeneration. For example,…
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• The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease February 26, 2021 Neurobiol Dis. 2021 Feb 23:105312. doi: 10.1016/j.nbd.2021.105312. Online ahead of print.ABSTRACTGene-environment interaction is implicated in the majority of idiopathic Parkinson's disease (PD) risk, and some of the most widespread environmental contaminants are selectively toxic to dopaminergic neurons. Pesticides have long been connected to PD incidence, however, it has become increasingly apparent that other industrial byproducts likely influence neurodegeneration. For example,…
• The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease February 26, 2021 Neurobiol Dis. 2021 Feb 23;153:105312. doi: 10.1016/j.nbd.2021.105312. Online ahead of print.ABSTRACTGene-environment interaction is implicated in the majority of idiopathic Parkinson's disease (PD) risk, and some of the most widespread environmental contaminants are selectively toxic to dopaminergic neurons. Pesticides have long been connected to PD incidence, however, it has become increasingly apparent that other industrial byproducts likely influence neurodegeneration. For example,…
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• Trichloroethylene: An Invisible Cause of Parkinson's Disease? March 20, 2023 J Parkinsons Dis. 2023;13(2):203-218. doi: 10.3233/JPD-225047.ABSTRACTThe etiologies of Parkinson's disease (PD) remain unclear. Some, such as certain genetic mutations and head trauma, are widely known or easily identified. However, these causes or risk factors do not account for the majority of cases. Other, less visible factors must be at play. Among these is a widely used industrial solvent and common…
• Trichloroethylene: An Invisible Cause of Parkinson's Disease? March 20, 2023 J Parkinsons Dis. 2023;13(2):203-218. doi: 10.3233/JPD-225047.ABSTRACTThe etiologies of Parkinson's disease (PD) remain unclear. Some, such as certain genetic mutations and head trauma, are widely known or easily identified. However, these causes or risk factors do not account for the majority of cases. Other, less visible factors must be at play. Among these is a widely used industrial solvent and common…
• Trichloroethylene: An Invisible Cause of Parkinson's Disease? March 20, 2023 J Parkinsons Dis. 2023;13(2):203-218. doi: 10.3233/JPD-225047.ABSTRACTThe etiologies of Parkinson's disease (PD) remain unclear. Some, such as certain genetic mutations and head trauma, are widely known or easily identified. However, these causes or risk factors do not account for the majority of cases. Other, less visible factors must be at play. Among these is a widely used industrial solvent and common…
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