Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition

Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition
Nat Neurosci. 2022 Jun 20. doi: 10.1038/s41593-022-01094-6. Online ahead of print.ABSTRACTChannelrhodopsins are used widely for optical control of neurons, in which they generate photoinduced proton, sodium or chloride influx. Potassium (K+) is central to neuron electrophysiology, yet no natural K+-selective light-gated channel has been identified. Here, we report kalium channelrhodopsins (KCRs) from Hyphochytrium catenoides. Previously known gated potassium channels are ... read more
Source: PubMedPublished on 2022-06-21By Elena G Govorunova